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  • Comprehensive Analysis of Silencing Mutants Reveals Complex Regulation . . .
    A genome-wide study of DNA methylation in a comprehensive list of Arabidopsis mutants implicated in gene silencing and histone modification reveals that different pathways regulate DNA methylation site specifically, and the study uncovers new factors that regulate DNA methylation
  • Comprehensive Analysis of Silencing Mutants Reveals . . . - ScienceDirect
    Here we have surveyed the methylomes of a comprehensive list of 86 Arabidopsis gene silencing mutants by generating single-nucleotide resolution maps of DNA methylation We find that DNA methylation is site specifically regulated by different factors Furthermore, we have identified additional regulators of DNA methylation
  • Impacts of DNA methylases and demethylases on the . . . - Springer
    Here, we analyzed the bisulfite sequencing and mRNA sequencing data from Arabidopsis (de)methylase mutants met1, cmt3, drm1 2, ddm1, ros1-4, and rdd to investigate how DNA (de)methylases influence the DNA methylation and expression of Arabidopsis ET pathway genes At least 32 genes are found to involved in Arabidopsis ET pathway by text mining
  • Moving targets: Mechanisms regulating siRNA production and DNA . . .
    DNA methylation is a conserved modification that must be precisely regulated during development to facilitate its roles in silencing transposable elements and regulating gene expression In plants, DNA methylation changes during reproduction are widely documented and, in many cases, the underlying mechanisms are well understood In somatic tissues, the diversity of methylation patterns are
  • Comprehensive Analysis of Silencing Mutants Reveals Complex Regulation . . .
    Here we have surveyed the methylomes of a comprehensive list of 86 Arabidopsis gene silencing mutants by generating single-nucleotide resolution maps of DNA methylation We find that DNA methylation is site specifically regulated by different factors Furthermore, we have identified additional regulators of DNA methylation
  • Post-transcriptional gene silencing triggers dispensable DNA . . .
    These 24-nt siRNAs produced by DICER-LIKE 3 (DCL3) processing of double-stranded RNA (dsRNA) are loaded onto ARGONAUTE 3 (AGO3), AGO4, AGO6 or AGO9 to guide transcriptional gene silencing (TGS) and RNA-directed DNA methylation (RdDM) of homologous DNA, mostly at transposon and repetitive loci (1–3)
  • Co-targeting RNA Polymerases IV and V Promotes Efficient
    Comprehensive investigation into the genetic pathway of RNA-directed DNA methylation in Arabidopsis defines epistatic relationships and allows for efficient manipulation of DNA methylation to specifically modify developmental phenotypes
  • DNA methylation-linked chromatin accessibility affects genomic . . . - PNAS
    Here, we profiled chromatin accessibility in 18 DNA methylation mutants, including met1, ddm1, fwa, nrpd1, nrpe1, nrpe1 nrpd1, dms3, drm1 drm2, cmt2, cmt3, cmt2 cmt3, drm1 drm2 cmt2 cmt3 (ddcc), drm3, idn2, idn2 idl1 idl2, suvr2, ago4, and frg1 frg2
  • Transgenerational effect of mutants in the RNA-directed DNA . . . - Springer
    While 4x mutants in NRPE1, RDR2, DCL3, and DRM2 suppress the triploid block [35], no suppressive effect of those mutants was found in the osd1 background [16] However, mutants in the Pol IV component NRPD1 could similarly suppress the triploid block in 4x and osd1 backgrounds [16, 35], suggesting that there is a difference in the response to





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