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  • Aristolochic acid - Wikipedia
    Aristolochic acid Aristolochic acids (English: əˌrɪstəˈloʊkɪk ) are a family of carcinogenic, mutagenic, and nephrotoxic phytochemicals commonly found in the flowering plant family Aristolochiaceae (birthworts) Aristolochic acid (AA) I is the most abundant one [1]
  • Aristolochic Acids - Cancer-Causing Substances - NCI
    What are aristolochic acids? Aristolochic acids are a group of acids found naturally in many types of plants known as Aristolochia (birthworts or pipevines) and some types of plants known as Asarum (wild ginger), which grow worldwide
  • PLANTS CONTAINING ARISTOLOCHIC ACID - Pharmaceuticals - NCBI Bookshelf
    For the purpose of this Monograph, unless otherwise specified, the term ‘aristolochic acids’ refers to an extract of Aristolochia species comprising a mixture of aristolochic acid I and its demethoxylated derivative, aristolochic acid II
  • Herb Danger - Aristolochic Acid Warning - MedicineNet
    Based on new information, the Food and Drug Administration (FDA) is advising consumers to immediately discontinue use of any botanical products containing aristolochic acid These products may have been sold as "traditional medicines" or as ingredients in dietary supplements
  • Herbal products containing aristolochic acids: A call to revisit the . . .
    Aristolochic acids (AA) are a compound that is abundant in Aristolochia plants Previous studies have reported that AAs exert several therapeutic effects and have been commonly used to treat a variety of illnesses, such as eczema, pneumonia, stroke, hepatitis, snakebites, arthritis, gout and coronary artery diseases
  • Aristolochia (Birthwort): The Deadly Truth Behind a Traditional Remedy . . .
    These compounds trigger a specific disease called Aristolochic Acid Nephropathy (AAN) This is a rapid fibrosis of the renal tissue that destroys the kidneys’ ability to filter blood, leading to end-stage renal failure requiring dialysis or transplant This phenomenon was historically documented as Balkan Endemic Nephropathy 3
  • Overview of aristolochic acid nephropathy: an update - PMC
    Aristolochic acid nephropathy (AAN) is a rapidly progressive renal interstitial fibrosis caused by medical or environmental exposure to aristolochic acid (AA) Since the outbreak of AAN in Belgium was reported nearly 30 years ago, the safety of
  • Aristolochic acid-associated cancers: a public health risk in . . . - Nature
    Aristolochic acids (AAs) are a group of naturally occurring compounds present in many plant species of the Aristolochiaceae family
  • Systematic Overview of Aristolochic Acids: Nephrotoxicity . . .
    Aristolochic acids (AAs) are a group of toxins commonly present in the plants of genus Aristolochia and Asarum, which are spread all over the world Since the 1990s, AA-induced nephropathy (AAN) and upper tract urothelial carcinoma (UTUC) have been reported in many countries
  • Aristolochic acid-associated cancers: a public health risk in need of . . .
    Our Review aims to systematically present the historical and current evidence for the mutagenicity and carcinogenicity of AA, and the effect of removing sources of AA exposure on cancer incidence trends





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