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gussy    音标拼音: [g'ʌsi]
n. 装饰;粉饰

装饰;粉饰


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  • The enzymology of the human prostanoid pathway
    Both PTGS1 and PTGS2 catalyze the conversion of arachidonic acid to PGH 2 through similar mechanisms The reaction mechanism proposed for PTGS1 is based on that presented for the ovine enzyme; the 92 5% sequence homology makes this a good model for the human enzyme
  • Prostaglandin H synthases: members of a class of quasi-linear threshold . . .
    Prostaglandin H synthases (PTGS or COX, also known as prostaglandin endoperoxide G H synthase or PGHS) combine two enzymatic activities, first a cyclooxygenase activity that converts arachidonic acid (or similar polyunsaturated fatty acids) to prostaglandin G 2 (PGG 2), a hydroperoxide intermediate, then a peroxidase activity that reduces PGG 2
  • The PTGS2 COX2-PGE2 signaling cascade in inflammation: Pro or anti? A . . .
    We presently review the effects of PTGS2 COX2-PGE 2 cascade in different inflammatory contexts, focusing on pancreatic beta cells subjected to T1DM conditions and discuss its potential exploitation as therapeutic target for the autoimmune pathology Prostaglandins are synthetized via the arachidonic acid (AA) pathway
  • Flipping the cyclooxygenase - Journal of Lipid Research
    Two prostaglandin (PG) H synthases encoded by Ptgs genes, colloquially known as cyclooxygenase (COX)-1 and COX-2, catalyze the formation of PG endoperoxide H 2, the precursor of the major prostanoids
  • Cyclooxygenase-1 - Wikipedia
    Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase (COX), is the key enzyme in prostaglandin biosynthesis It converts free arachidonic acid, released from membrane phospholipids at the sn-2 ester binding site by the enzymatic activity of phospholipase A2, to prostaglandin (PG) H2
  • Macrophage responses to lipopolysaccharide are modulated by a feedback . . .
    Prostaglandin E 2 (PGE 2) is the major downstream product of COX-2-mediated arachidonic acid metabolism in many cells PGE 2 increases blood flow, vascular permeability and nociception,
  • Entry - *176805 - PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 1; PTGS1 - OMIM
    Prostaglandin-endoperoxide synthase (PTGS; EC 1 14 99 1; fatty acid cyclooxygenase; PGH synthase) is the key enzyme in prostaglandin biosynthesis The cyclooxygenase activity of the enzyme is inhibited by nonsteroidal antiinflammatory drugs (NSAID) such as aspirin and endomethacin
  • Prostaglandins - StatPearls - NCBI Bookshelf - National Center for . . .
    Synthetically derived prostaglandins can be used to modulate numerous processes in the body This activity will highlight the mechanism of action, indications, side effect profile, contraindications, and other information needed for healthcare team members
  • Genes for prostaglandin synthesis, transport and inactivation are . . .
    PTGS1 is considered to mainly have constitutive expression in uterine tissues, whereas PTGS2 is an inducible enzyme In some species, parturition is associated with increased intrauterine PTGS2 expression and increased PG release (Dong et al , 1996; Gibb et al , 2000; Wu et al , 2001)
  • COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and . . .
    Nonsteroidal anti-inflammatory drugs (NSAIDs) target the prostaglandin H synthase enzymes, cyclooxygenase (COX)-1 and -2, and reduce colorectal cancer risk Genetic variation in the genes encoding these enzymes may be associated with changes in colon and rectal cancer risk and in NSAID efficacy
  • Prostaglandin-endoperoxide synthase (PTGS1 and PTGS2) expression and . . .
    Monkey OSE expresses mRNA for PTGS1, PTGS2, and all PGE synthases and produces PGE 2 both before and 36 hours after hCG Detection of PTGS1, but not PTGS2, protein in OSE in vivo supports the hypothesis that PTGS1 is the enzyme responsible for PGE 2 production by primate OSE in vivo
  • Prostaglandin 2 biosynthesis and metabolism - commerce. bio-rad. com
    Prostaglandin E synthase (PGES) and Prostaglandin E synthase 2 (PGES2) catalyze the transformation of PGH2 to 15-hydroperoxy-PGE1 , , Cytochrome P450, family 4, subfamily F, polypeptide (CYP4F12) reduces PGH2 to 20-hydroxy-prostaglandin H1 , This enzyme also catalyzes the reduction of PGE2 to 9-oxo-PGF2alpha
  • PTGS1 - an overview | ScienceDirect Topics
    Prostaglandin E2 (PGE2), a subtype of prostaglandin, has been shown to play a pivotal role in cancer initiation and progression via its receptor PTGER (prostaglandin E receptor, also known as EP) 1–4
  • In situ imaging reveals disparity between prostaglandin localization . . .
    Although our current results show overlapping localization of PGD 2, arachidonic acid, and 2-AG with Ptgs1, the role of COX1 is obscured by the fact that Ptgs2 can compensate for Ptgs1 loss
  • Prostaglandin-Endoperoxide Synthase 2 (PTGS2) in the Oviduct: Roles in . . .
    Prostaglandin-endoperoxide synthase 2 (PTGS2), also known as cyclooxygenase 2 (COX-2), is the rate-limiting enzyme in the production of prostaglandins (PGs) and plays an essential role during early pregnancy, including ovulation, fertilization, implantation, and decidualization





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