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  • AN OVERVIEW ON MUCOSAL DRUG DELIVERY SYSTEM - ijnrd. org
    Mucosal drug delivery systems represent a promising approach for achieving targeted and sustained drug release through the body’s mucous membranes These delivery systems exploit the absorptive properties of the mucosa in areas such as the oral, nasal, vaginal, ocular, and gastrointestinal tracts
  • Nasal Epithelial Cells: Function in Health and Disease
    Nasal epithelial cells are the gatekeepers of the respiratory system, forming the initial line of defense as the lining of the nasal cavity, or nasal mucosa As the first point of contact with the air we breathe, this cellular barrier interacts with a constant stream of environmental factors, including pathogens, allergens, and pollutants
  • Mechanisms and solutions for nasal drug delivery a narrative review
    There are three principal factors that influence the ex-tent to which drugs can be absorbed through the nasal lining, namely the physico-chemi-cal characteristics of the drug molecule itself, the action of the mucociliary system within the nose, and the presence of any factors increas-ing nasal absorption
  • Nasal Drug Delivery System - IJPS Journal
    Nasal route gives good absorption of small molecules, than that of large molecules can be increased by absorption promoters In this article an overview of intranasal drug delivery with its various aspects like factors affecting nasal absorption, strategies to improve bioavailability are discussed 1 ADVANTAGES :1,3,6,7
  • An Overview of the Anatomy and Physiology of Nasal Passage from Drug . . .
    The nasal mucosa’s rapid clearance and tight junctions limit absorption and permeability Therefore, the sensitivity of the nasal mucosa acts as a guide for creating drug formulations Ideal formulations must have permeation and mucoadhesive enhancing agents, higher viscosity, and certain pH levels
  • NASAL DRUG DELIVERY- AN OVERVIEW - IJPSR
    In addition, nasal drug delivery circumvents the issues of poor and slow absorption, first pass hepatic metabolism, blood brain barrier Intranasal administration can be used to deliver small polar molecules, hormones, vaccines, proteins and peptides Despite the several potential advantages the nasal route has certain limitations
  • (PDF) On Nasal Drug Delivery System - Academia. edu
    Due to the high permeability, high vasculature, low enzymatic environment of nasal cavity and avoidance of hepatic first pass metabolism are well suitable for systemic delivery of drug molecule via nose The present review describes nasal delivery systems in recognizing to its potential and limits
  • Mucosal Drug Delivery Flashcards - Quizlet
    What are the advantages of mucosal drug delivery? What are the disadvantages of mucosal drug delivery? - secreted by goblet cells - diffusion barrier for drugs - target for mucoadhesion Function: coat entry points, protects epithelial tissue, keeps membrane moist - extra-large molecules either membrane bound or secreted
  • Nasal mucosa - Structure, Function, Anatomy, Location
    The nasal mucosa is a specialized tissue that lines the nasal cavity It is a moist, soft membrane composed primarily of epithelial cells, blood vessels, and mucous-producing glands This lining is covered by a thin layer of mucus, which helps maintain hydration and acts as a barrier





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