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frump    音标拼音: [fr'ʌmp]
n. 守旧者,邋遢的女人

守旧者,邋遢的女人

frump
n 1: a dull unattractive unpleasant girl or woman; "she got a
reputation as a frump"; "she's a real dog" [synonym: {frump},
{dog}]

Frump \Frump\, v. t. [Cf. Prov. E. frumple to wrinkle, ruffle,
D. frommelen.]
To insult; to flout; to mock; to snub. [Obs.] --Beau. & Fl.
[1913 Webster]


Frump \Frump\, n.
1. A contemptuous speech or piece of conduct; a gibe or
flout. [Obs.] --Beau. & Fl.
[1913 Webster]

2. A cross, old-fashioned person; esp., an old woman; a
gossip. [Colloq.] --Halliwell.
[1913 Webster]


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  • Hypophosphatasia (HPP) Symptoms, Causes Treatment
    Hypophosphatasia (HPP) is a rare genetic condition that softens your bones and can cause you to lose your teeth earlier than usual It has seven major forms that range in severity and age of onset
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    Hypophosphatasia is an inherited disorder that affects the development of bones and teeth This condition disrupts a process called mineralization, in which minerals such as calcium and phosphorus are deposited in developing bones and teeth
  • Hypophosphatasia - Wikipedia
    Hypophosphatasia is a rare disease that has been reported worldwide and appears to affect individuals of all ethnicities [3] The prevalence of severe hypophosphatasia is estimated to be 1:100,000 in a population of largely Anglo-Saxon origin
  • Diagnosis and Treatment of Hypophosphatasia - PMC
    Hypophosphatasia (HPP) is a rare inherited metabolic disorder characterized by deficient activity of tissue-nonspecific alkaline phosphatase (TNAP) caused by variants in the ALPL gene
  • Hypophosphatasia (HPP) - Childrens Hospital of Philadelphia
    Hypophosphatasia, sometime shortened to HPP, is a rare inherited disorder that affects the development of bones and teeth In children and adults with hypophosphatasia, the bones and teeth do not absorb enough calcium and phosphorus
  • Hypophosphatasia - Symptoms, Causes, Treatment | NORD
    Hypophosphatasia (HPP) is a rare genetic disorder characterized by impaired mineralization (“calcification”) of bones and teeth Problems occur because mineralization is the process by which bones and teeth take up calcium and phosphorus required for proper hardness and strength
  • Hypophosphatasia: MedlinePlus Genetics
    Hypophosphatasia is an inherited disorder that affects the development of bones and teeth This condition disrupts a process called mineralization, in which minerals such as calcium and phosphorus are deposited in developing bones and teeth
  • Hypophosphatasia | Home
    Learn about hypophosphatasia (HPP), its symptoms, and its effect on infants, children, and adults Find resources and tools to support your HPP journey
  • Hypophosphatasia patients find answers and treatments
    What is hypophosphatasia? HPP is a genetic disorder caused by mutations that interfere with the production and activity of an enzyme called alkaline phosphatase, which is essential for the proper development and ongoing health of bones and teeth





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