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heaps    音标拼音: [h'ips]
炼焦堆

炼焦堆

heaps
adv 1: very much; "thanks heaps"
n 1: a large number or amount; "made lots of new friends"; "she
amassed stacks of newspapers" [synonym: {tons}, {dozens},
{heaps}, {lots}, {piles}, {scores}, {stacks}, {loads},
{rafts}, {slews}, {wads}, {oodles}, {gobs}, {scads},
{lashings}]


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  • Risk factors of metachronous brain metastasis in patients with EGFR . . .
    Background NSCLC patients with EGFR mutation were at a higher incidence of developing brain metastasis (BM) Patients with BM are associated with high mortality Reducing BM incidence becomes increasingly significant for NSCLC patients to achieve prolonged survival The aim of the study was to explore the possible risk factors of developing metachronous BM during EGFR-TKIs treatment, and to
  • LncRNA MEG3 promotes cisplatin sensitivity of cervical cancer cells by . . .
    Background Cervical cancer (CC) is a common gynecological malignancy worldwide Some patients perform serious resistance after chemotherapy, and long-stranded non-coding RNA MEG3 is reported to be involved in the regulation of chemoresistance in many solid tumors However, its involvement in cervical adenocarcinoma has not been reported Methods Hela cell lines, cisplatin-resistant cell lines
  • Promoter hypermethylation of HS3ST2, SEPTIN9 and SLIT2 combined with . . .
    Background Non-muscle-invasive bladder cancer (NMIBC) is a high incidence form of bladder cancer (BCa), where genetic and epigenetic alterations occur frequently We assessed the performance of associating a FGFR3 mutation assay and a DNA methylation analysis to improve bladder cancer detection and to predict disease recurrence of NMIBC patients Methods We used allele specific PCR to
  • Constitutive activation of the ERK pathway in melanoma and skin . . .
    Background Constitutive activation of the ERK pathway, occurring in the vast majority of melanocytic neoplasms, has a pivotal role in melanoma development Different mechanisms underlie this activation in different tumour settings The Grey phenotype in horses, caused by a 4 6 kb duplication in intron 6 of Syntaxin 17 (STX17), is associated with a very high incidence of cutaneous melanoma, but
  • A parallel-group randomized clinical trial of individually tailored . . .
    Background The effect of early palliative care and rehabilitation on the quality of life of patients with advanced cancer has been only sparsely described and needs further investigation In the present trial we combine elements of early, specialized palliative care with cancer rehabilitation in a 12-week individually tailored, palliative rehabilitation program initiated shortly after a
  • Prognostic nutritional index predicts lateral lymph node metastasis and . . .
    BMC Cancer 2018;18 (1):390 Article PubMed PubMed Central Google Scholar Offi C, Romano RM, Cangiano A, Candela G, Docimo G Clinical significance of neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, platelet-to-lymphocyte ratio and prognostic nutritional index in low-risk differentiated thyroid carcinoma
  • 17β-estradiol induces stearoyl-CoA desaturase-1 expression in estrogen . . .
    Background To sustain cell growth, cancer cells exhibit an altered metabolism characterized by increased lipogenesis Stearoyl-CoA desaturase-1 (SCD-1) catalyzes the production of monounsaturated fatty acids that are essential for membrane biogenesis, and is required for cell proliferation in many cancer cell types Although estrogen is required for the proliferation of many estrogen-sensitive
  • Relevant factors for policy concerning comprehensive genomic profiling . . .
    Background Comprehensive genomic profiling (CGP) can identify targets beyond standard of care, potentially revolutionizing personalized cancer management However, conducting well designed studies in this rapidly evolving field is complex and demands time and investments Consequently, the total added value of CGP remains uncertain Clinical benefit and costs often are driving factors in





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