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  • Understanding How Microorganisms Respond to Acid pH Is . . .
    Damage to the genetic material by acid pH or organic acids, often caused indirectly by generating reactive oxygen species (Schellhorn and Stones, 1992; Kim et al , 2006; Bruno-Bárcena et al , 2010), can trigger a DNA damage response in both bacteria and yeast (Ribeiro et al , 2006; Jeong et al , 2008)
  • Bacterial acid stress response: from cellular changes to . . .
    Most bacteria are neutralophiles but can survive fluctuations in pH in their environment Herein, we provide an overview of the adaptation of several human, soil, and food bacteria to acid stress, mainly based on next-generation sequencing studies, highlighting common and specific strategies
  • Bacterial Metabolism - Medical Microbiology - NCBI Bookshelf
    In bacteria, glycolysis represents one of several pathways by which bacteria can catabolically attack glucose The glycolytic pathway is most commonly associated with anaerobic or fermentative metabolism in bacteria and yeasts In bacteria, other minor heterofermentative pathways, such as the phosphoketolase pathway, also exist
  • Acetic acid stress in budding yeast: From molecular . . .
    Acetic acid stress represents a frequent challenge to counteract for yeast cells under several environmental conditions and industrial bioprocesses The molecular mechanisms underlying its response have been mostly elucidated in the budding yeast Saccharomyces cerevisiae, where acetic acid can be ei …
  • Microbial response to acid stress: mechanisms and applications
    Some yeast and bacteria maintain a relatively stable and neutral intracellular pH (pH i) in the presence of constantly changing extracellular pH (pH ex) and generate unfixed proton gradients (Siegumfeldt et al 2000) However, a constant pH gradient is more favorable to most acid-tolerant microbes
  • Microbial response to acid stress: mechanisms and applications
    Some yeast and bacteria maintain a relatively stable and neutral intracellular pH (pH i) in the presence of constantly changing extracellular pH (pH ex) and generate unfixed proton gradients (Siegumfeldt et al 2000) However, a constant pH gradient is more favorable to most acid-tolerant microbes
  • Physiological responses to acid stress by Saccharomyces . . .
    All the acids studied impaired growth and inhibited glycolytic flux, and caused oxidative stress and accumulation of trehalose However, trehalose may play a role other than protecting yeast cells from acid-induced oxidative stress





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