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phage    
n. 抗菌素

抗菌素

phage
n 1: a virus that is parasitic (reproduces itself) in bacteria;
"phage uses the bacterium's machinery and energy to produce
more phage until the bacterium is destroyed and phage is
released to invade surrounding bacteria" [synonym:
{bacteriophage}, {phage}]

bacteriophage \bacteriophage\ n. sing. & pl.
a virus which infects bacteria; -- also colloquially called
{phage} in laboratory jargon.

Note: Bacteriophages are of many varieties, generally
specific for one or a narrow range of bacterial
species, and almost every bacterium is susceptible to
at least one bacteriophage. They may have DNA or RNA as
their genetic component. Certain types of
bacteriophage, called

{temperate bacteriophage}, may infect but not kill their host
bacteria, residing in and replicating either as a plasmid
or integrated into the host genome. Under certain
conditions, a resident temperate phage may become induced
to multiply rapidly and vegetatively, killing and lysing
its host bacterium, and producing multiple progeny. The
{lambda phage} of {Eschericia coli}, much studied in
biochemical and genetic research, is of the temperate
type.
[PJC] bacteriophagic



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  • Mayo patient with life-threatening multidrug-resistant infection . . .
    Mark was Mayo Clinic's fourth patient to receive the investigational phage therapy treatment under a compassionate use basis He has since formed a special bond with Mayo's first phage therapy patient, who also was facing a potential amputation from a knee-joint replacement infection
  • In a first, Mayo Clinic treats cardiology patient with phage therapy
    Dr Suh had previously used phage therapy to treat several orthopedic patients with recalcitrant bacterial infections in their prosthetic joint replacement devices But this would be the first time she would use the investigational therapy on a cardiology patient with an infection in a left ventricular assist device
  • Phage therapy shows potential for treating prosthetic joint infections
    ROCHESTER, Minn — Bacteriophages, or phages, may play a significant role in treating complex bacterial infections in prosthetic joints, according to new Mayo Clinic research The findings suggest phage therapy could provide a potential treatment for managing such infections, including those involving antibiotic-resistant microbes The research is published in the July issue of Clinical
  • Mayo Clinic patients find hope in individualized medicine in 2023
    In a first, Mayo Clinic treats cardiology patient with phage therapy Mark Ulland, a Mayo Clinic patient, recently received a lifesaving combination of phage therapy followed by a heart transplant It is the first time Mayo Clinic has ever used phages to treat a cardiology patient
  • 7 ways Mayo Clinic is leading to cure, connect and transform health . . .
    Mayo is also supporting a new phage therapy program to offer a potential life-saving alternative to antibiotics Phages are naturally occurring viruses that target and kill specific bacterial cells, including those that have grown resistant to multiple antibiotics
  • Human Genome Project — ‘A race to the starting line’
    Furthermore, the Center is focusing on phage therapy, the use of natural viruses and genetics to treat complex bacterial infections This will become increasingly important as antibiotic resistant infections increase across the globe
  • Pandemic vs. Endemic vs. Outbreak: Terms to Know
    Understanding epidemiological terms such as pandemic, endemic, and outbreak can be confusing, especially as more news emerges about Zika virus and dengue fever Mayo Clinic infectious diseases specialist Dr Pritish Tosh offers some insight What is the difference among a pandemic, endemic and an outbreak? A pandemic refers to a global epidemic — one that has spread over […]
  • Celebrating Mayo Clinic women in medicine on International Women’s Day
    Dr Suh has a special interest in bacteriophages as a novel therapeutic for the treatment of infections, particularly multi-drug resistant and biofilm-mediated infections She treated Mayo Clinic’s first phage therapy patient and is heading efforts to create the Mayo Clinic Phage Therapy Program and run clinical trials
  • Weve only just begun to glimpse what is possible - and more thought . . .
    Phage therapy could provide a potential treatment strategy " - Gina Suh, M D , infectious diseases specialist, Mayo Clinic "The advantage of looking at the blood is we may in fact find tumor related material before the onset of a malignancy





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