Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits This chapter primarily focuses on the behavioral and neurobiological analyses of PCP-induced sensitization, neurotoxicity, and alterations in NMDA receptor expression during the brain growth spurt – a critical period of development
The Neuropharmacology of PCP: Mechanisms and Implications This article explores the intricate mechanisms by which PCP affects the brain, including its impact on neurotransmitter systems, and the implications for neurological and psychiatric disorders
Cognitive Deficits from Meth and PCP Use Are Generated By a Common . . . Scientists in the Department of Neurobiology, School of Biological Sciences, investigated how methamphetamine and phencyclidine (PCP or “angel dust”), which take effect by activating different targets in the brain, induce a similar reduction in cognitive ability
Neuroscience for Kids - PCP - UW Faculty Web Server PCP affects multiple neurotransmitter systems in the brain For example, PCP inhibits the reuptake of dopamine, norepinephrine and serotonin and also inhibits the action of glutamate by blocking NMDA receptors Some types of opioid receptors in the brain are also affected by PCP
PCP Side Effects: Short Long-Term Phencyclidine Effects Adolescents and young adults are particularly vulnerable to PCP’s damaging effects Because their brains are still actively developing, especially in areas responsible for judgment, impulse control, and emotional regulation, they’re more susceptible to lasting neurological damage